Neurolucida® User guide

Version 2024

About Neurolucida software

The Neurolucida system is specifically designed for accurately tracing neuronal structures directly from histological specimens and generating quantitative morphometric data. Neuroscientists around the world trust Neurolucida as the gold standard for producing accurate anatomical models that can be quantitatively analyzed in hundreds of different ways to address perplexing biological questions. With over 6000 citations, research conducted with the help of the Neurolucida system has led to hundreds of advances in the understanding of neurodegenerative diseases, neuropathy, memory, and behavior.

  • If you are a new user, you may want to tour the software interface here.

What's new

See the What's new page or view the release notes.

Trace structures

Resources

Computer-system requirements

Guidelines on computer-system requirements are available here.

The computer-processing power needed to run Neurolucida depends on the size, compression, and structure of the image and data files that you are evaluating. We recommend that you review the computer-system requirements before you start working with Neurolucida or if the software crashes while you are using it.