What's new

See the current Release Notes or all Release Notes for Vesselucida 360.

  • Surface effects of traced objects in the 3D environment now include enhanced options with the ability to include a legend, change colors, and adjust transparency for customized visualization and figures. This includes surface options for vessels, puncta, and markers.

  • New contour-type legend can be displayed in the 3D window for enhanced visualization.

  • Typical process width setting is now available in the Automatic tracing Display seeds setup to help guide the tracing algorithms.

  • Existing puncta can now be excluded from subsequent detections with different detection parameters.

  • After applying image filters using the Batch Pipeline, you can now begin tracing right away.

  • Added the ability to save an image crop in .tif format increasing flexibility for use in other programs.

  • The Image Scaling dialog box that appears when opening images now has updated, more helpful information.

  • Added support for .dcm image files.

SPARC Users

The Stimulating Peripheral Activity to Relieve Conditions (SPARC) program seeks to accelerate development of therapeutic devices that modulate electrical activity in nerves to improve organ function.

  • Term import and search has been added to tree and vessel classification for easier navigation of the anatomical terminology list.

Recent improvements

  • New Batch Pipeline enables easy-to-use batch processing for image filtering and detection/modeling of vessels.

  • Now you can save your 3D settings for automatic detection and reconstruction of vessels and puncta for use in the Batch Pipeline

  • New Pipelines ribbon now houses features previously located in the Automatic section of the Trace Ribbon

  • Improved & expanded image support

  • New automatic, smart image-optimization preference for low-signal images available

  • Improvements to puncta detections, including recognition of manually traced vessels/puncta in other color channels for proximity-based detection of puncta.

  • The Subvolume tool is now restricted by the bounds of the image

  • In the Cell detection workflow, the image source is automatically updated based on the image modality selected

  • Image montage can now assemble images of varying x/y sizes

  • Faster image and data handling: Vesselucida 360 software uses a new approach to image and data handling based on intelligent image loading, maximized concurrent usage of CPU cores, multiple levels of data caching, and efficient use of RAM and GPU resources. Overall software function and performance is improved, highlights include:

    • Image- and data-files load noticeably faster than in previous releases

    • You'll notice that Vesselucida 360 software responds more quickly as you work; it handles hundreds of thousands of data points simultaneously.

    • Image adjustments are immediately displayed in both the 2D and 3D Environment—without clicking any buttons.

  • Simpler software authorization: Vesselucida 360 autofills the online Authorization Request Form with information about your computer system. Just fill in your name and contact information, plus the name of your PI to submit the form.

  • More powerful Drag and drop file opening: Load your image files by dragging and dropping onto the Vesselucida 360 window. The new Image Opener makes it easy to specify how you want the software to handle your image files.

  • New Puncta detection tool in the 3D environment replaces the synapse detection feature in previous releases.

  • New subvolume tool in the 3D environment enables you to easily and systematically divide images/image stacks for analysis. It replaces the large volume reconstruction feature present in previous releases.

  • New Channel panel enables you to select one or more color channels to view, hide, and associate with structures in your images.

  • You can now clip tracings to partial projection view in the 3D environment. In addition, tracing with partial projection will automove the image in the Z orientation.

  • The default image-save format is now .xml.

Recent enhancements for SPARC users

  • SPARC vocabulary term lists displayed as ontological trees.

  • Network licensing is now available for SPARC researchers.
  • New Quick surface tool partially automates the process of creating contours to map interior and exterior surfaces.
  • SPARC Vocabulary Services launch when opening a file, rather than when starting Vesselucida 360 software.
  • Updates to how Vesselucida 360 software links to and interacts with the SciCrunch database to use SPARC vocabulary, including: