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MBF Bioscience News

MBF Bioscience >  Blog
January 11, 2017

Uncovering the role of microglia in fetal alcohol spectrum disorders

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Stereology, Neuron Reconstruction
Comments

[caption id="attachment_6526" align="aligncenter" width="800"] Representative images of Iba-1+ microglia in the postnatal day 10 rat hippocampus. Image courtesy of Anna Klintsova, PhD.[/caption] Children born with fetal alcohol spectrum disorders face a range of physical and cognitive impairments including long-term deficits in learning, behavior, and immune function. In a paper published in Neuroscience, Dr. Anna Klintsova and her lab at the University of Delaware report that activation...

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December 29, 2016

ScanImage Enables Cutting Edge Visual Cortex Research

by Pasang
in 2 Photon, Scientific Applications & Use Cases, ScanImage®, MBF Products & Service Solutions, Multi-Photon Microscopy Solutions, Multi-Photon Imaging
Comments

Complex imaging and experimental tasks must happen quickly in a smooth workflow so that experiments can be performed within the time constraints imposed by working with behaving animals. ScanImage is the software of choice for controlling your scanning microscopy experiments because it provides robust cutting edge imaging features coupled with the ability to automate and time workflows like no other application can. A key feature...

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September 15, 2016

Stereological Study Reveals Neuron and Glia Proliferation in Hippocampus of Lithium-Treated Mice

by Pasang
in Company News, Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, Stereology
Comments

The optical fractionator probe was used to quantify the number of neurons and glia in the dentate gyrus   Doctors have used lithium to treat patients with bipolar disorder since the 1970s. Known for its efficacy in stabilizing patients' moods by regulating manic episodes, lithium is also associated with a decreased risk of suicide. But while this naturally occurring element is the most widely prescribed medication for...

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July 6, 2016

Scientists Observe Differences Between Brains of Stressed and Unstressed Rats After Fear Conditioning

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, Neuron Reconstruction
Comments

[caption id="attachment_6403" align="aligncenter" width="632"] This figure illustrates the separate and combined effects of acute stress and fear conditioning/extinction on dendritic morphology of pyramidal neurons in the infralimbic region of medial prefrontal cortex. Each neuron shown is a composite made up of apical (blue) and basilar (orange) arbor near the mean of the group. The apical and basilar arbors of each composite are from different neurons....

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May 26, 2016

Neurolucida 360 v2.7: A minor release with major new features

by Pasang
in Company News, Software Applications For Quantitive Analysis, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®360
Comments

The 3 algorithms in Neurolucida 360 were used in combination to create a smooth, accurate reconstruction   Minor releases typically don't include new features, but Neurolucida 360 isn't an ordinary piece of software. Neurolucida 360 v2.7 has many new features and improvements, including: A new automatic tracing algorithm - Rayburst Crawl Capture videos of your rotating neuron reconstructions for presentations and publications New backbone length analysis for dendritic spines Improved handling of images...

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May 18, 2016

MBF Bioscience to Open European Headquarters in the Netherlands

by Pasang
in Company News, Additional Subject Matter
Comments

MBF Bioscience announced today that it will open a European Sales and Support office in Delft, the Netherlands. Masha Stern, who has been the Manager of Technical Support and Training at MBF Bioscience headquarters in Vermont for 11 years, will become the Managing Director of MBF Europe. The new office is scheduled to open September 2016.   “Our new European Office is a result of the continually...

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April 25, 2016

MBF Bioscience Awarded Two Patents in 2016

by Pasang
in WormLab®, Company News, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, C.elegans Behavioral Analysis Solutions, Awards, C. Elegans, Worm Tracking
Comments

  We continue our history of innovation and invention as the U.S. Patent and Trademark Office awards us two patents. The first is for WormLab - our unique worm tracking software that gives researchers an enormous amount of behavioral data about a single worm or multiple worms, even as they go through omega bends, reversals, and entanglements. The second is for our radial shock wave technology...

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April 5, 2016

Iron Deficiency Worsens Fetal Alcohol Spectrum Disorders

by Pasang
in Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, Stereology, Optical Fractionator
Comments

[caption id="attachment_6326" align="aligncenter" width="600"] An immunostained image of myelin basic protein in the cerebella of a mouse brain with an iron-sufficient diet compared with the brain of a mouse exposed to alcohol and fed an iron-insufficient diet. It shows the reduced cerebellar size due to the ID-alcohol combination. Green is MBP immunostain, blue is DAPI for nuclei. Image courtesy of Susan Smith, PhD.[/caption]   If a pregnant...

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February 17, 2016

Dr. Robert Ogilvie to Receive the Henry Gray Distinguished Educator Award

by Pasang
in Biolucida, Company News, Scientific Applications & Use Cases, MBF Products & Service Solutions, Big Image Data Management Solutions, Additional Subject Matter, Medical Education
Comments

Aspiring medical doctors and life science researchers in the U.S. learn histology to understand the cellular organization of tissues and organs. In the past, microscopes were the only equipment available for viewing cells and other microscopic structures in tissue specimens. Now, more and more students are learning histology with virtual microscope slides – high-resolution digital images of tissue specimens that can be viewed on a...

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February 11, 2016

Genetic Mutation Accelerates CTE Pathology

by Pasang
in Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, Stereology, Optical Fractionator
Comments

[caption id="attachment_6175" align="aligncenter" width="480"] Phosphorylated tau pS422 immunoreactive profiles (dark brown) in the cortex of P301S mice after repetitive mild TBI. Image courtesy of Dr. Leyan Xu, Department of Pathology, Johns Hopkins University.[/caption]   Over the course of a football game or a boxing match, athletes may experience a series of mild concussions. Some of these athletes develop a condition known as chronic traumatic encephalopathy (CTE), a...

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