Commonly used as a human anaesthetic and animal tranquilizer, the experimental drug ketamine became famous in the last two decades as a hallucinatory club drug known as “Special K.” Now, researchers at Yale University say the drug is beneficial in treating depression by increasing synaptic connections in parts of the brain that regulate mood and cognition. Dr. Ronald Duman, who uses Stereo Investigator and Neurolucida at...
Read More
A baby cries and her mother's maternal instincts kick in. She picks her baby up, rocks her, feeds her. Changes in a new mother's brain compel her to act in ways that ensure her baby's survival. Researchers at the Hebrew University of Jerusalem are working on learning more about those changes. Their recent focus is on the olfactory bulb – a region of the brain...
Read More
MBF Bioscience was featured in an episode of Emerging Science, a television series that features Vermont scientists who expand human knowledge and help solve problems around the world. The episode explored the link between traumatic brain injury and post traumatic stress disorder in military personnel coming back from war. MBF Bioscience President Jack Glaser and Staff Scientist Susan Hendricks give us some perspective from a research standpoint...
Read More
Long-time MBF customers at the University of Rochester Medical Center are considered leading experts in researching myelin diseases. They recently published a review article in Science titled “Glial Progenitor Cell-Based treatment and Modeling of Neurological Disease” in which they featured output from Stereo Investigator in the Figure 2 section to illustrate chimeric brains. {Glial Progenitor Cell–Based Treatment and Modeling of Neurological Disease Steven A. Goldman, Maiken Nedergaard, and Martha S....
Read More
Approximately 11,000 Americans become paralyzed from spinal cord injuries each year with little hope for recovery. But new research from the University of California at San Diego saw some promising results. The research team, led by MBF Bioscience customer Dr. Mark Tuszynski and Dr. Paul Lu saw movement in paralyzed rats after grafting a gel containing neural stem cells to the rats' injured spinal cords. According...
Read More
When it comes to preferred neuron reconstruction and neuron tracing systems, Neurolucida “dominated the last decade” according to a paper published earlier this year in Frontiers in Neuroscience. The paper, “Digital reconstructions of neuronal morphology: three decades of research trends" (Halavi et al, 2012), offers an overview of the history of digital neuron reconstruction and presents research trends on specific animal species, brain regions, neuron types,...
Read More
In the early 1960s, our company co-founder Dr. Edmund Glaser and his long time collaborator and friend Dr. Hendrik Van der Loos made some sketches on a paper tablecloth in the faculty dining room at John Hopkins Hospital, in Baltimore Maryland. That early diagram of a microscope included novel elements like transducers and a mechanical stage, and gave shape to their ideas about a faster way...
Read More
Blue Brain Project researchers have hit an important milestone in their quest to create a virtual model of the human brain. They figured out how to accurately predict the location of synapses in the neocortex; and Neurolucida played an important part. In a paper published last week in PNAS, the research team led by Dr. Henry Markram at the Brain Mind Institute at the Ecole Polytechnique Fédérale...
Read More Dr. Daniel Peruzzi, staff scientist, shares his thoughts below: Customers often ask Staff Scientists at MBF Bioscience why it is sometimes difficult to reproduce certain published stereological results. For example, we get the question, “The estimates that I make of cell number in the region I’m researching do not match numbers reported in the literature. Can you help me understand why?” To solve this dilemma, we encourage...
Read More
During a chicken embryo's twenty-one days of incubation, its eyes develop in astonishing ways. Muscles form, neurons branch, innervation occurs. Researchers at Dr. Rae Nishi's lab at the University of Vermont, including two MBF Bioscience staff scientists Julie Simpson, Ph.D. and Julie Keefe, M.S. are studying the development of a chicken embryo's nervous system. Their specific focus is on the behavior of neurons in the...
Read More