[caption id="attachment_5617" align="alignnone" width="700"] This image stack was used in the study to analyze spine density. Image courtesy of Tara Chowdhury, Ph.D. first author of the study.[/caption] To find out how anorexia nervosa changes the brain, scientists at New York University are studying a rat model of the disease called activity-based anorexia (ABA). Previously, they discovered that ABA rats develop unusually robust dendritic branching of neurons...
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When neuroscientists started studying neurons in 3D, it revolutionized brain science. Now, for the first time, scientists are using this same technology to study the human placenta, and they've made some fascinating new discoveries about its structure. Using Neurolucida to create 3D reconstructions of villous trees – three-dimensional structures in the placenta that facilitate gas and nutrient exchange between the fetus and mother – researchers in...
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[caption id="attachment_5560" align="aligncenter" width="800"] Almeida-Suhett et al saw delayed loss of GABAergic interneurons in the BLA within the first week after mild CCI. (Representative photomicrographs of GAD-67 immunohistochemically stained GABAergic interneurons in the BLA of sham (left), 1-day CCI (middle), and 7-day CCI (right) animals. Total magnification is 630x; scale bar, 50 µm.)[/caption] Soldiers, athletes, and other individuals who suffer a traumatic brain injury often develop...
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People with Alzheimer's disease suffer from severe memory loss and often have problems focusing, reasoning, and communicating. About half of all Alzheimer's patients also experience delusions and hallucinations, this is called Alzheimer's disease with psychosis, and scientists at the University of Pittsburgh are learning more about this severe version of the disease. In a recent study, researchers at Dr. Robert Sweet's lab zeroed in on a...
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A baby laughs at an elephant at the zoo. A toddler runs across a beach. Small children make memories all the time, but how many will they recall as the years pass? Maybe none at all. The phenomenon is called “infantile amnesia,” and scientists may have pinpointed a reason for why it occurs – neurogenesis. Researchers at the Hospital for Sick Children in Toronto say that...
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After an initial spinal cord injury, a cascading series of secondary events continues to do damage to the nervous system. One particularly damaging event is the death of oligodendrocytes—neuroglial cells that help protect and support the central nervous system. Scientists are learning more about the mechanisms involved in this process in the hope that their research may lead to the development of new therapeutic treatments...
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Researchers have identified two strains of mutant C. elegans that lose the majority of their dopaminergic neurons in adulthood, a characteristic of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. The two strains of mutant C. elegans (ot337 and ot477) showed normal development of dopaminergic neurons, however these neurons began to progressively decline in adulthood; and the deterioration was not an occurrence of the normal aging process, the authors say in...
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The deepest parts of the ocean are dark. For marine animals living one thousand feet below sea level and lower, the absence of light makes it challenging to find food, attract a mate, and identify predators. Some animals make their own light through a process called bioluminescence. Others have adapted in ways that help them detect light in an environment beyond the reach of the sun's...
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We are happy to announce that Biolucida, our learning management software, is now hosting the Iowa Virtual Slidebox. This vast repository of digitized tissue specimens is open to the public and is free of charge. Virtual slides in this collection are used by educators around the world to teach histopathology and histology. “Educators and students will now have easier and quicker access to virtual slides from...
Read More The human brain undergoes extraordinary development in utero, with major growth continuing throughout childhood, especially during the first year. Scientists know a lot about how the neurons and circuits of the human brain develop in infancy, but a lack of specific knowledge about key elements has left doctors mystified by certain childhood disorders like SIDS and autism. Neuroscientists at Ludwig-Maximillians-University of Munich have made new revelations...
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