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Software & Microscope Integrated Systems

MBF Bioscience >  Blog > MBF Products & Service Solutions  > Software & Microscope Integrated Systems (Page 2)
September 23, 2020

Curcumin Lowers Neuroinflammation in Mouse Model

by Pasang
in Software Applications For Quantitive Analysis, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®360, Alzheimer’s Disease
Comments

Scientists at Western Sydney University used Stereo Investigator and Neurolucida 360 to quantify cells in a mouse model of neuroinflammation after feeding mice two different curcumin formulations. Some inflammation is normal in a healthy mammalian brain. But as the brain ages, processes can break down, leading to chronic neuroinflammation. This can develop into Alzheimer’s disease, dementia, and other neurodegenerative diseases.   Scientists at Prof. Gerald Muench’s lab, at...

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July 1, 2020

New Therapy May Aid Heart Repair After Heart Attack

by Pasang
in Software Applications For Quantitive Analysis, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Vesselucida®360, Vesselucida®Explorer
Comments

Researchers Quantify Improvement in Heart Vasculature with Vesselucida 360 and Vesselucida Explorer Cells need oxygen to survive, but during a heart attack, blood flow is restricted and cardiac cells can’t get the oxygen they need to stay alive. A new therapy, developed by researchers at the Coulombe Lab at Brown University may be able to provide the heart with the support it needs to recover after...

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January 18, 2019

MBF Bioscience research team contributes novel dendritic spine analysis in study published in Science

by Pasang
in Company News, Software Applications For Quantitive Analysis, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®360
Comments

Combination of new microscopy and expansion tissue preparation methods facilitate better and faster analysis of subcellular neural elements. Today, the journal Science published a paper authored by a research team led by Dr. Ed Boyden of MIT and Nobel Prize recipient Dr. Eric Betzig of Janelia Research Campus. Among the authors are MBF Bioscience Scientific Director Dr. Susan Tappan and Senior Software Engineer Alfredo Rodriguez. In the...

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September 19, 2018

Scientists Discover New “Rosehip” Neuron in Human Brain

by Pasang
in Software Applications For Quantitive Analysis, Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®Explorer, 3D Reconstruction
Comments

Neurolucida and Neurolucida Explorer Used for 3D Reconstruction and Quantitative Analysis Researchers used Neurolucida to reconstruct a newly discovered type of neuron found only in the human brain, according to a study published in the journal Nature Neuroscience. Known as “rosehip” neurons because of the way they resemble a rose after its petals have fallen off, these cells feature compact, bushy axonal arborizations.   Found in the first...

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November 30, 2017

NeuroMorpho.Org Releases Nearly 10,000 New Neuron Reconstructions and Neurolucida leads the way

by Pasang
in Software Applications For Quantitive Analysis, Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Neurolucida®360, 3D Reconstruction, Neuron Reconstruction
Comments

[caption id="attachment_6839" align="aligncenter" width="632"] Image Courtesy: Bob Jacobs, Ph.D. , Colorado College[/caption]   With the release of its new version on November 28, NeuroMorpho.org adds 9,987 new images to its archive, bringing its impressive collection of digitally reconstructed neurons to 80,012.   Scientists used MBF Bioscience’s software, Neurolucida and Neurolucida 360, to reconstruct the majority of these cells. In fact, 64 times more neurons were reconstructed with MBF Bioscience...

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November 7, 2017

MBF Bioscience unveils whole mouse brain automatic region delineation and cell mapping with the Allen Mouse Brain Reference Atlas

by Pasang
in Company News, Software Applications For Quantitive Analysis, Neurolucida®, Biolucida, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, Artificial Intelligence, MBF Products & Service Solutions, BrainMaker®, Additional Subject Matter, NeuroInfo®, Big Image Data Management Solutions, 3D Reconstruction
Comments

[caption id="attachment_6830" align="aligncenter" width="632"] An experimental coronal mouse brain section automatically aligned to the Allen Mouse Brain Reference Atlas[/caption]   Analyzing cellular populations within specific anatomies in brain images requires expertise in both neuroanatomy and cellular identification. This typically involves a scientist comparing experimental images with a reference atlas and manually delineating anatomical regions and marking cell populations within. NeuroInfo®, a revolutionary new technology from MBF Bioscience,...

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September 26, 2017

Diet Restriction Slows Neurodegeneration and Extends Lifespan of DNA-Repair-Deficient Mice

by Pasang
in Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Stereology
Comments

  DNA damage occurs in human cells at a constant rate. These cells are usually able to repair themselves, but sometimes deficiencies in certain genes cause the repair process to shut down. When damaged DNA isn't fixed, mutations can occur that cause accelerated aging or cancerous tumors to form (Hoeijmakers, 2009). Scientists at Erasmus University Medical Center in Rotterdam have found a way to slow down...

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April 12, 2017

MBF Bioscience Unveils Redesigned Interface for Neurolucida and Stereo Investigator version 2017

by Pasang
in Neurolucida®, Company News, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter
Comments

Neuroscientists can now analyze the size and complexity of neurons and collect unbiased stereology data with greater speed and efficiency We are happy to announce the release of Neurolucida and Stereo Investigator version 2017. This version features a completely revamped user interface that’s intuitive and easy to navigate.   “Neurolucida and Stereo Investigator version 2017 are completely redesigned to improve the user experience and increase productivity,” said Jack...

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February 16, 2017

Exercise changes astrocytes and eases symptoms of neurodegenerative disorders

by Pasang
in Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, Alzheimer’s Disease, 3D Reconstruction
Comments

Astrocytes (GFAP) in the dentate gyrus of a mouse hippocampus. Image courtesy of Dr. Ahmad Salehi, Stanford University.   It is well known that physical exercise eases the symptoms of neurodegenerative disorders like Alzheimer’s disease and helps to prevent their onset. Researchers at Stanford University are working on figuring out how it happens.   In their study, published in the journal Brain Structure and Function, scientists in Dr....

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January 11, 2017

Uncovering the role of microglia in fetal alcohol spectrum disorders

by Pasang
in Neurolucida®, Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Stereology, Neuron Reconstruction
Comments

[caption id="attachment_6526" align="aligncenter" width="800"] Representative images of Iba-1+ microglia in the postnatal day 10 rat hippocampus. Image courtesy of Anna Klintsova, PhD.[/caption] Children born with fetal alcohol spectrum disorders face a range of physical and cognitive impairments including long-term deficits in learning, behavior, and immune function. In a paper published in Neuroscience, Dr. Anna Klintsova and her lab at the University of Delaware report that activation...

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