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Throughout my career, I've been driven by a singular goal: to advance scientific research by making cutting-edge tools accessible to researchers worldwide. Today, I'm thrilled to share news that I believe will significantly impact our field.   In just a few days, at the Society for Neuroscience meeting in Chicago, we will be unveiling SLICE – our new affordable light sheet microscope that truly redefines what's possible...

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In the fast-evolving field of neuroscience, groundbreaking research on the intricate workings of the vertebrate brain yields new information every day. A recent study published in the Journal of Neuroscience describes the establishment of an approach for better contextualization of proteins identified through proteomic analyses to identify candidate proteins for functional validation testing. The authors examined human synaptic processes from well-characterized human post-mortem samples and...

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The democratization of neuroscience is a movement that aims to make neuroscience research more accessible and inclusive to everyone. This movement is based on the principles of open science and aims to make neuroscience research more transparent, collaborative, and accessible to researchers around the world.   At MBF Bioscience, democratizing neuroscience has been part of our DNA since our founding 35 years ago when we launched Neurolucida....

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In their recent publication, Jeffrey Demas and co-authors introduced “Light Beads Microscopy”, an important technological breakthrough in 2 photon microscopy. The authors demonstrated how their innovative microscopy approach can be used to observe the activity of individual neurons in vivo in large volumes of mouse cortex, offering a long-sought approach to studying brain encoding.   Light Beads Microscopy is a new method of two-photon microscopy optimized for...

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The question of whether an increased lifespan is associated with increased quality of life has been a topic of interest in the field of aging research. While there is evidence that improved somatic maintenance in model organisms can lead to increased longevity, recent studies have suggested that long-lived mutants may actually spend a higher percentage of their lives in an unhealthy state compared to non-mutants....

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ScanImage software from MBF Bioscience, along with the accompanying vDAQ acquisition and control card with analog to digital, digital to analog, breakout board, is built to control many combinations of hardware in order to carry out in-vivo imaging on a cellular scale. This makes it possible to observe the neural activities, such as those indicated by calcium concentration or voltage changes, of specific neuronal types...

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Using specimens that were collected over three decades from zoos, researchers at Humboldt University of Berlin examined facial motor control in African and Asian elephants. As described in their recent paper in Science Advances, they examined cell number, size, and position in the facial nucleus; conducted quantitative nerve tracing, and performed comparative analyses with other animals and between the two elephant types. The researchers found...

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