Williston, VT - In 2020, the National Institutes of Health awarded $71.6 million in grants and contracts to Vermont research institutions, supporting job creation and economic vitality in the Green Mountain State. The University of Vermont, the state’s largest employer, led the list of recipients, but right behind UVM is another, lesser known powerhouse in the biomedical research community—MBF Bioscience. An award-winning Vermont business, MBF Bioscience engineers...
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Our state-of-the-art software for performing unbiased stereology is getting an upgrade. Faster, stronger, and better, has been a theme for us lately, as we improve our products across the board, but one place where this is especially striking is in Stereo Investigator. Set for release this spring, the new and improved Stereo Investigator will include a new imaging engine, display engine, automatic camera alignment, automatic lens calibration, the double disector, and live video zooming.  “I’m...
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MBF Bioscience is expanding our two photon and laser scanning technology capabilities by acquiring Vidrio Technologies. Vidrio and MBF share a deep passion for helping scientists reveal the fundamental structures and functions of the brain. Our teams are committed to serving the neuroscience community by providing innovative hardware and software tools to help researchers achieve their goals. We are driven to do our part to move...
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We suspect 2020 will always be remembered as the year of big, unexpected questions. Questions like, “How will we do our work together if we’re all working from our homes?" “When will we be able to move around freely again?” “How quickly will the economy bounce back post pandemic?” Questions like these have challenged each and every one of us to remain optimistic, curious, and mindful about what the...
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For Immediate Release Williston, VT (February 11th, 2021)—MicroDynamix™software version 2021 is now available. This state-of-the-art dendritic-spine analysis application enables users to visualize and quantify spine morphology over time using powerful algorithms and detection methods. Developed with input and support from the National Institute of Mental Health (NIMH), the new version of MicroDynamix software makes it easier than ever for neuroscientists to obtain accurate 4D dynamic analyses...
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For Immediate Release Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D.  The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...
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For Immediate Release  Williston, VT (December 10, 2020) —NeuroInfo®is the most advanced software for mapping brain sections, 3D volumes and cell populations into a standardized atlas reference space. Optimized to enable researchers to work far more efficiently, the new NeuroInfo update means faster, more efficient measurements and mapping workflows. The new version of NeuroInfo includes: Identification and delineation of brain regions in experimental mouse-brain sections Automatic cell detection using deep learning to recognize and count specific neuronal subtypes Performance optimizations that...
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Dr. Bob Jacobs has traced his 5,000th and final neuron. “It’s a good stopping point I think,” says the long-time MBF Bioscience customer, collaborator, and friend, who is retiring from research in December. Dr. Jacobs has made significant advances in the fields of neuroanatomy and neuroethology over the course of his 30-year career. And the team at MBF Bioscience is grateful for the collaborative relationship we’ve...
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Researchers at Colorado College may have identified a new neuropathological hallmark of Chronic Traumatic Encephalopathy (CTE). Their findings, published in the Journal of Comparative Neurology, describe overall dendritic atrophy across cortical neurons and greater morphological variability in CTE brains compared to controls. A neurodegenerative disorder characterized by late-onset symptoms like depression, confusion, and memory loss, CTE is caused by repeated impacts to the brain. The disease...
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For Immediate Release: Williston, VT — October 6, 2020 — Big science produces big data. At laboratories around the world, researchers from every scientific discipline face a similar problem — how to manage the massive image files generated by large-scale experimental imaging workflows. MBF Bioscience has solved this problem by leveraging our scientific imaging expertise to produce MicroFile+, a freely available software tool for the scientific community....
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