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Aspiring medical doctors and life science researchers in the U.S. learn histology to understand the cellular organization of tissues and organs. In the past, microscopes were the only equipment available for viewing cells and other microscopic structures in tissue specimens. Now, more and more students are learning histology with virtual microscope slides – high-resolution digital images of tissue specimens that can be viewed on a...

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  The U.S. Small Business Administration recently published a success story about MBF Bioscience. The article highlights our success using federal Small Business Innovation Research (SBIR) grants to develop innovative products that help advance science. MBF Bioscience has a distinguished R&D program that develops cutting-edge tools for scientific research.   The SBIR grants have helped MBF Bioscience develop tools such as Neurolucida, the most widely used system for...

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How the brain works and how the brain is affected by disease are mysteries in large part because neurons are so dynamic, numerous, and complex. Neurolucida 360, a revolutionary, new software product from MBF Bioscience, enables neuroscientists to uncover more information about neurons at a faster rate.   “Neurolucida 360 is a technological revolution” says Jack Glaser, President of MBF Bioscience. “It is the state-of-the-art tool for neuroscientists to analyze...

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[caption id="attachment_5991" align="aligncenter" width="632"] Dr. Paul Manger's new system developed by MBF Bioscience for analyzing large mammalian brain specimens[/caption]   Dr. Paul Manger, Research Professor at the University of the Witwatersrand, South Africa, studies the brain anatomy of various animals to better understand the relationship between brain structure and function. Some of the mammals he studies have very large brains that don't fit under a conventional research...

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In 2014 researchers used Stereo Investigator in 698 peer-reviewed papers - citing it almost three times more than all other stereology systems combined. Researchers tell us they use Stereo Investigator because: it works with many different microscopes and imaging technologies it provides unbiased data about neuron populations and regions of interest it comes with strong technical and research support provided by MBF Bioscience [caption id="attachment_5790" align="alignnone" width="1394"] source: google scholar[/caption] Dr. Mark West, co-developer of...

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MBF Bioscience received a prestigious Tibbetts Award during a ceremony at the White House on May 16. The Tibbetts Award recognizes MBF Bioscience for a number of accomplishments including: technological innovation, serving federal Research and Development needs, encouraging diverse participation, and increasing the practical commercial use of federal research.   The Tibbetts Award is given to companies who participate in the Small Business Innovation Research program which is run by...

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[caption id="" align="alignright" width="189"] Overall view of the computer microscope developed by Drs. van der Loos and Glaser (circa 1965).[/caption] Prior to the computer microscope era, quantitative neuro-anatomical studies were performed using the camera lucida method, an optical method allowing the scientist to see the neurons as if reflected on the piece of paper on which she will trace. These studies were painstaking and extremely time-consuming....

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  [caption id="attachment_3412" align="aligncenter" width="238"] Original figures published with permission from Dr. Ed Glaser[/caption]   In 1963, Dr. Ed Glaser (co-founder of MBF Bioscience) and Dr. Hendrik van der Loos were at the John Hopkins Medical School putting the final touches on the first computer microscope, an analog computer connected to a light microscope. It was described as a system for attaching X-Y-Z transducers to a microscope stage,...

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Thirty-six high school students passionate about neuroscience will be competing at the 4th annual Vermont Brain Bee on February 9th, 2013 at the University of Vermont College of Medicine. Participants will be asked questions about a wide variety of topics: anatomy and development, learning and memory, stress, types of research, neurogenerative disorders, etc. They will also get the opportunity to engage in neuroscience activities and...

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MBF Bioscience was featured in an episode of Emerging Science,  a television series that features Vermont scientists who expand human knowledge and help solve problems around the world.   The episode explored the link between traumatic brain injury and post traumatic stress disorder in military personnel coming back from war.   MBF Bioscience President Jack Glaser and Staff Scientist Susan Hendricks give us some perspective from a research standpoint...

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