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MBF Bioscience Blog

MBF Bioscience >  Blog
November 14, 2012

Stereo Investigator Graphics Displayed in Science Review Article

by Pasang
in Company News, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter
Comments

Long-time MBF customers at the University of Rochester Medical Center are considered leading experts in researching myelin diseases. They recently published a review article in Science titled “Glial Progenitor Cell-Based treatment and Modeling of Neurological Disease” in which they featured output from Stereo Investigator in the Figure 2 section to illustrate chimeric brains. {Glial Progenitor Cell–Based Treatment and Modeling of Neurological Disease Steven A. Goldman, Maiken Nedergaard, and Martha S....

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November 7, 2012

UCSD Researchers Make Paralyzed Rats Move Again

by Pasang
in Additional Subject Matter
Comments

Approximately 11,000 Americans become paralyzed from spinal cord injuries each year with little hope for recovery. But new research from the University of California at San Diego saw some promising results.   The research team, led by MBF Bioscience customer Dr. Mark Tuszynski and Dr. Paul Lu saw movement in paralyzed rats after grafting a gel containing neural stem cells to the rats' injured spinal cords. According...

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October 24, 2012

Neurolucida is the Leading Software for Neuron Reconstruction and Neuron Tracing

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction, Neuron Reconstruction
Comments

When it comes to preferred neuron reconstruction and neuron tracing systems, Neurolucida “dominated the last decade” according to a paper published earlier this year in Frontiers in Neuroscience. The paper, “Digital reconstructions of neuronal morphology: three decades of research trends" (Halavi et al, 2012), offers an overview of the history of digital neuron reconstruction and presents research trends on specific animal species, brain regions, neuron types,...

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October 9, 2012

We’re Kicking off a Year of Celebrations in Honor of the Computer Microscope’s 50th Anniversary

by Pasang
in Company News, Additional Subject Matter
Comments

In the early 1960s, our company co-founder Dr. Edmund Glaser and his long time collaborator and friend Dr. Hendrik Van der Loos made some sketches on a paper tablecloth in the faculty dining room at John Hopkins Hospital, in Baltimore Maryland. That early diagram of a microscope included novel elements like transducers and a mechanical stage, and gave shape to their ideas about a faster way...

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September 26, 2012

Dr. Henry Markram’s Team Uses Neurolucida in New Blue Brain Study

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction, Neuron Reconstruction
Comments

Blue Brain Project researchers have hit an important milestone in their quest to create a virtual model of the human brain. They figured out how to accurately predict the location of synapses in the neocortex; and Neurolucida played an important part.   In a paper published last week in PNAS, the research team led by Dr. Henry Markram at the Brain Mind Institute at the Ecole Polytechnique Fédérale...

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September 12, 2012

Study Review: Dr. Daniel Peruzzi Highlights Best Publication Practices by Analyzing a New Stereological Study

by Pasang
in Company News, Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, Stereology
Comments

Dr. Daniel Peruzzi, staff scientist, shares his thoughts below:   Customers often ask Staff Scientists at MBF Bioscience why it is sometimes difficult to reproduce certain published stereological results. For example, we get the question, “The estimates that I make of cell number in the region I’m researching do not match numbers reported in the literature. Can you help me understand why?”   To solve this dilemma, we encourage...

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August 16, 2012

UVM Scientists Use Neurolucida and Stereo Investigator to Study Neurons in the Avian Iris

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction, Stereology, Neuron Reconstruction
Comments

During a chicken embryo's twenty-one days of incubation, its eyes develop in astonishing ways. Muscles form, neurons branch, innervation occurs. Researchers at Dr. Rae Nishi's lab at the University of Vermont, including two MBF Bioscience staff scientists Julie Simpson, Ph.D. and Julie Keefe, M.S. are studying the development of a chicken embryo's nervous system. Their specific focus is on the behavior of neurons in the...

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August 8, 2012

Dr. Eric Kandel Studies Schizophrenia with a Transgenic Mouse and a Neuroanatomical Eye

by Pasang
in Additional Subject Matter
Comments

  A crux of Dr. Eric Kandel's career has been the integration of psychiatric with biological research. After earning a degree in psychiatry from NYU Medical School, he turned his attention to the brain's molecular structure, and later pioneered a reductionist approach to neurobiology by using the Aplysia sea slug as his model organism.   An MBF Bioscience customer for many years, Dr. Kandel's research on learning and...

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June 28, 2012

A Look Inside Dr. Mark West’s New Book, Basic Stereology for Biologists and Neuroscientists

by Pasang
in Scientific Applications & Use Cases, Stereology
Comments

  Stereology has come a long way since Dr. Mark West started using the method of quantitative analysis in his research. The assumption-based or model-based stereological methods of the 1970s have been replaced by the more sophisticated design-based or unbiased stereological methods used today. Dr. West, a Professor of Medical Neurobiology at Aarhus University in Denmark and author of the most cited scientific papers on the...

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June 14, 2012

Vermont Public Television visits MBF Bioscience

by Pasang
in Company News, Additional Subject Matter
Comments

  A Vermont Public Television crew brought several cameras into our Williston office today to learn more about MBF Bioscience and Henry Markram, a long time customer of MBF.   Dr. Markram, director of the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, is using Neurolucida to create a complete simulation of the 89 billion neurons and 100 trillion connections in the human brain by 2023....

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