Neurolucida®Explorer

In the fast-evolving field of neuroscience, groundbreaking research on the intricate workings of the vertebrate brain yields new information every day. A recent study published in the Journal of Neuroscience describes the establishment of an approach for better contextualization of proteins identified through proteomic analyses to identify candidate proteins for functional validation testing. The authors examined human synaptic processes from well-characterized human post-mortem samples and...

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Neurolucida and Neurolucida Explorer Used for 3D Reconstruction and Quantitative Analysis Researchers used Neurolucida to reconstruct a newly discovered type of neuron found only in the human brain, according to a study published in the journal Nature Neuroscience. Known as “rosehip” neurons because of the way they resemble a rose after its petals have fallen off, these cells feature compact, bushy axonal arborizations.   Found in the first...

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Scientists hypothesize that during puberty, experiences influence brain development in ways that shape brain structure and even behavior in adulthood. One type of experience that often arises in the minds of pubescent teens and adolescents is sex. But a study published in the journal Hormones and Behavior suggests engaging in sexual activity too soon could be detrimental to the adult brain, and may lead to...

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Life's little pleasures often elude those suffering from depression, including rats, who show little interest in sugar water after experiencing stress. This behavior leads scientists to speculate that the illness might be characterized by a defect in the brain's neural reward circuit.   Recent research focuses on a key element of this circuit – the nucleus accumbens (NAc), part of the brain region known as the ventral...

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    A monkey spots a mango and part of its brain lights up. The action takes place in the inferior temporal cortex, part of the brain that's essential to object recognition. Using retrograde tracing and anatomical imaging, scientists at the National Institute of Neuroscience, and the RIKEN Brain Science Institute in Japan identified two interwoven, yet distinct, systems within the region's complex circuitry.   “Our anatomical findings provide evidence...

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Scientific research shows that women are twice as likely as men to develop stress disorders. Why are women more sensitive than men to stress? A recent research study presents new evidence that estrogen could play a role.   The symptoms of disorders like major depressive disorder and post traumatic stress disorder lead neuroscientists to speculate that a dysfunction occurs in the way the medial prefrontal cortex connects...

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When your mouth is dry, your joints are stiff, or your heart is inflamed because your immune system is attacking your own body, chances are you're suffering from a little stress. A recent study shows that there may be physiological reasons why patients with autoimmune diseases experience increased levels of anxiety.   Scientists at the City University of New York Medical School, Columbia University, and the University...

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Myelin, which insulates axons in the central nervous system is produced by oligodendrocytes. But not all oligodendrocytes are equal.   Led by Dr. Jonathan Vinet of the Université Laval in Quebec, scientists have identified three different types of oligodendrocytes in the mouse hippocampus: "ramified," "stellar," and "smooth."   Each type displayed varying morphological characteristics, mainly in shape, volume, and branching behavior, which led the researchers to believe that the...

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